Cotula cinerea Del. belongs to the family Asteraceae. It is widely used in the traditional medicinal system for the treatment of various ailments such as colic. Cotula cinerea Delile [family COMPOSITAE ] (stored under name); Verified by Not on Brocchia kotschyi; Cotula kotschyi; Cotula cinerea; Brocchia cinerea. Abstract: The phytochemical investigation of Cotula cinerea Del. afforded eighteen Keywords: Cotula cinerea Del.; Asteraceae; Flavonoids; Germacranolide.
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In the genus was subdivided by George Bentham  into three sections. These compounds could act individually or in a synergic manner.
Vogel Cotula filifolia Thunb. Subscribe to Table of Contents Alerts.
Those of Salvia verbenaca were collected on March at the locality called Ain Aouda, in the Rabat region, Morocco. In this work we were interested in exploring the potential cytotoxicological effect of Cotula cinerea and Salvia verbenaca from Morocco.
BioMed Research International
Indexed in Science Citation Index Expanded. Topics Discussed in This Paper. Higher concentrations were needed in the case of Salvia verbenaca extracts which showed the weakest cytotoxic effects. Chemical composition and Anticandidal properties of the essential oil isolated from aerial parts of Cotula Cinerea: Mouzdahir A Huile essentielle de Santolina africana Jord.
Voucher specimens of both plants were deposited in the herbarium of the Botany Department of this institution. Cotulaa current widely used cancer treatments such as surgery, radiotherapy, systemic therapy, and chemotherapy are very expensive and cause several side clnerea adverse effects [ 4 ].
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For the town, see Cotula, Tennessee. Further investigations regarding cktula identification of bio-actives molecules responsible for these effects are needed. Moreover, a molecule could have an effect on one type of tumor and not on others. Cotula is the largest genus found in the Southern Hemisphere of the tribe Anthemideae.
Cotula – Wikipedia
Indeed, plants are rich sources of new compounds from which some secondary metabolites have been shown to cofula anticancer properties [ 5 — 7 ]. In the case of the Vero tumor cell line, Table 1 reveals that Cotula cinerea essential oil showed the highest cytotoxic capacity with the lowest IC 50 value References Publications referenced by this paper.
Table of Contents Alerts. Further studies are obviously needed to cineea the exact mechanism of Cotula cinerea in cytotoxic activity. Phillips Cotula pterocarpa DC. Salvia verbenaca is a Mediterranean plant currently belonging to the Lamiaceae family.
Antiproliferative activity at different concentrations of the essential oil and different extracts of Cotula cinerea top and Salvia verbenaca bottom against RD cell line by MTT assay. Nevertheless, the Cotula cinerea essential oil can act cotuls various mechanisms.
It is thus important and imperative to find more effective drugs with a shorter application period. Views Read Edit View history. Hilliard Cotula loganii Hutch. The obtained results raise then the possibility of a potential use of Cotula cinerea as a source of potent anticancer products.
El Btaouri et al. The essential oil and the ethyl acetate extract showed moderate cytotoxic effects Prolonged cancer treatment is generally costly to patients and complicates patient follow-up in hospital. In other projects Wikimedia Commons Wikispecies. Morocco is rich in medicinal plants on which some studies have been focused on antitumor activities [ 7 — 10 ]. Antiproliferative activity at different concentrations of the essential oil and different extracts of Cotula cinerea top and Salvia verbenaca bottom against Vero cell line by MTT assay.
Exploring alternative sources of new antitumor agents with specific targets is thus imperative and of great and crucial importance. The sections possess different basic chromosome numbers:.
Flavonoids from Cotula cinerea Del
In the same conditions and for the Vero cell line, the best cytotoxic effect was observed with the essential oil followed by the hexane, the ethyl acetate, and the n -butanol extracts.
Traditional forms of medicine, especially the herbal products deployed for centuries in many parts of the world, could be good alternative for scientific investigation due to their attributes against tumor cell lines. The essential oil of Cotula cinerea aerial parts was extracted by hydrodistillation using a Clevenger-type apparatus. Cotula macroglossa Bolus ex Schltr. Skip to search form Skip to cinerex content. The test is based on the biotransformation of MTT into formazan crystals by mitochondrial dehydrogenases of living cells.
Cotula cinerea which is of the Asteraceae family ccinerea a xerophytic plant widely distributed in sandy and desert grounds [ 11 ]. This study is expected to be beneficial for clinical and traditional applications for Cotula cinerea as a remedy against cancer and opens new perspectives for further investigations on other types of cancer cell lines.